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International Journal of Obesity, 2010 Fothergill et al., Persistent metabolic adaptation 6 years after the Biggest Loser competition

Ozempic and Rybelsus are not FDA approved to treat type 2 diabetes

Measure hematologic parameters on an annual basis and vitamin B12 measurements at 2- to 3-year intervals in patients on JANUMET XR and manage any abnormalities [see Adverse Reactions (6.1)]

It sits near the upper range

The clinical trial averages represent population-level expectations rather than individual guarantees

Prescription GLP-1 medications are usually taken once weekly, following medical guidance (15,16,17)