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Minimal change in appetite or weight

Individual dosage needs depend on GLP-1R receptor sensitivity, baseline insulin resistance, prior GLP-1 exposure, gastrointestinal function, and overall metabolic rate

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Margaret Morris, a professor of pharmacology at the University of New South Wales, said the JAMA Network study had several limitations, including adjusting for things like alcohol and substance misuse and off-label use, as well as a lack of information about dosages