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49 One of the underlying mechanisms of ROS-mediated tubulointerstitial injury is the exposure of tubular cells to LDL, which may result in tubulointerstitial damage due to NADPH oxidase-mediated ROS production

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When glutathione is involved in antioxidant reactions, it becomes the oxidized form, GSSG (glutathione disulfide)

So like it or not, nobody's willing to give the modern day conveniences at this point

Gibbs S