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The complex pathophysiology involves multiple features, such as metabolic disturbances, lipotoxicity, insulin resistance, chronic inflammation, fibrosis, intestinal function and the gut microbiome [57], and is closely associated with obesity, type 2 diabetes and the metabolic syndrome [58]

It can benefit those experiencing signs of ageing, dullness, or slower healing

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Rejuvenation Res 11(1):163175b