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2) The study performed by Li et al employed a multi-pronged experimental design, integrating human tissue analysis, in vitro cell culture, and in vivo animal models to comprehensively investigate the role of FOXO4 in age-related male fertility and the therapeutic potential of FOXO4-DRI

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IGF-1 LR3 activates the IGF-1 receptor (IGF-1R) to promote PI3K/Akt and MAPK/ERK signaling cascades

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