In clinical trials of Ozempic and Wegovy, nausea was reported in: 15.8% of people taking a 0.5 milligram (mg) dose 20.3% of people taking a 1 mg dose 44% of people taking a 2.4 mg dose Nausea is a common side effect of semaglutide, but its also seen with other similar medications in the GLP-1 receptor agonist class
The gastrointestinal symptoms serve a purpose, though they feel unpleasant
Participants were followed up for a total of 5 years post drug initiation
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According to a 2023 study, about 1% of Ozempic users and 0.7% of Saxenda users developed stomach paralysis, compared to 0.3% of those taking Contrave