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With careful monitoring, most digestive side effects, including changes in stool color, can be managed safely

As a result, propionic acid and its metabolic precursors accumulate, leading to the production of toxic metabolites such as 3-hydroxypropionic acid and methyl citrate, contributing to the nonspecific clinical manifestations and severity in PA

Declaration of Helsinki: ethical principles for medical research involving human subjects

10.1055/s-2008-1025758 137

However, large scale clinical trials have not demonstrated a clear benefit in slowing or preventing Alzheimers progression

Available at: who.int/genomics/anomalies/en/CFA-RegistryMeeting-2001.pdf