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61,62 The acetylation of p53 at certain sites hinders the phosphorylation of several serines located in the p53 NTD, which activates genes with high p53 affinity, including CDKN1A
13% decrease in subcutaneous fat mass 30% reduction of intra-abdominal fat mass 3-11% lean body mass increase 11-19% improvement in aerobic function Muscle strength increases between 7-19% After one year, participants saw overall body fat reduction, with the most significant results in the abdomen, with belly fat reduction at a notable 61%