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His main challenges were inconsistent dosing timing, weekend binge eating that crept back in once nausea faded, and stopping resistance training when he felt more fatigued in the first month

Patients with certain genetic variants may benefit from staying at a lower but consistent dose, while others respond better to the standard therapeutic range

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Abrupt stopping is medically discouraged because it can trigger intense rebound hunger, blood sugar swings in insulin-resistant individuals, and psychological distress from sudden cravings

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