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10.1074/jbc.c100512200 5 AlbistonA
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FOXO4-DRI is a D-amino acid retro-inverso peptide that disrupts the intracellular interaction between FOXO4 and p53 in senescent cells, triggering p53-mediated apoptosis selectively in senescent rather than healthy proliferating cells
Its about respecting the delicate nature of these powerful molecules and applying a level of precision that honors the research you're conducting
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The medication targets a fundamental biological driveappetite regulationrather than treating a disease state, which explains its broad applicability across different patient populations
10.1038/s41591-018-0109-4 211
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