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Small-study effects were examined via funnel plots, Eggers regression, and Beggs rank test, with trim-and-fill used as sensitivity analysis when indicated

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Grillo, A., Salvi, L., Coruzzi, P., Salvi, P., Parati, G

Pharmacological characterization To examine whether the potent weight loss observed in vivo after GLP-1MK-801 treatment is attributable to pharmacological synergy between GLP-1 and MK-801 or consequential to altered pharmacokinetic properties of the parent GLP-1 analogue, we designed and synthesized a conjugate comprising an inactive MK-801 surrogate 22 (Supplementary Fig

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