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As strength and power decline with age, patients and providers fear going on GLP-1s as trading obesity risk for early frailty
Natural GLP-1 is produced by the body, however, as we discussed earlier, it has a very short lifespan, and patients with T2D and other metabolic disorders can experience reduced secretion of the hormone or reduced sensitivity to it
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Both semaglutide and tirzepatide followed similar paths to the one retatrutide is on now
Melanie Jay, MD, a professor at New York University and the director of the NYU Langone Comprehensive Program on Obesity Research, points out that most brand-name drugs come in prefilled pens that make it relatively simple to dial up the right dose by twisting a knob