In addition to mucosal protection, research has explored the peptides influence on gastrointestinal motility regulation
IGF-1 as a Primary Mediator of Longitudinal Bone Growth Role of Locally Expressed IGF-1 Numerous studies have supported the importance of both GH and IGF-1 in mediating linear bone growth
[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Liu Y, Lu L, Yang H, Wu X, Luo X, Shen J, et al
2002 Apr;146(4):588-94
The key regulators of these alternate cycling events are the transcriptional co-activator and co-repressor molecules that function as accelerator and brake, respectively, to control target gene expression, in association with specific transcription factors
Key distinction from other GHRPs: Ipamorelin is considered the most selective GHSR agonist, with minimal effects on cortisol release (unlike GHRP-6, GHRP-2), prolactin release, and appetite stimulation (less than ghrelin)