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Available clinical evidence regarding L-carnitine supplementation in MASLD is summarized in Table 2, highlighting both reported metabolic benefits and the current limitations and heterogeneity of human studies

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Furthermore, as mentioned earlier, research combining vitamin D with other insulin-sensitizing substances like calcium, omega-3 fatty acids, or MI frequently shows greater metabolic advantages than vitamin D alone ( 3.4 Clinical evidence of vitamin D supplementation in PCOS: reproductive, metabolic, and OS outcomes Clinical trials investigating vitamin D supplementation in PCOS report a heterogeneous but progressively clarifying signal across reproductive, metabolic, and oxidative-inflammatory domains (122)

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