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Jabbour SA, Fras JP, Guja C, Hardy E, Ahmed A, hman P

Data are representative of four independent experiments and the K d values are calculated as the arithmetic mean and s.e.m

No multiple testing adjustment was applied to the statistical tests for the secondary outcomes

Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice

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