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(ii) -cyclodextrins increase the kinetic stability of the spin-adduct EBN/ SG

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Mutations in important arginine residues located on the p53-DNA-binding surface facilitate the loss of transcriptional activity and sequence-specific DNA binding

The activation of the JAKSTAT signaling pathway was suppressed by overexpressing aquaporin 1, indicating that aquaporin 1 improves aging and ageassociated dysfunction in TSPC by blocking the JAKSTAT signaling pathway [109]

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