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*Correspondence: Juan Huang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Methionine An amino acid that donates methyl groups, helping the liver package and export fat

A primary deficiency means that there is a genetic disorder that would cause the body to not produce sufficient levels of carnitine

Hagenacker et al., 2010

Fibromyalgia serves as the quintessential example, also observed in patients with early or advanced cirrhosis

They may also use modalities such as ice or heat to reduce inflammation and pain