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This may also imply that these drugs are most beneficial when used in conjunction with other interventions, such as lifestyle changes or other medications. Professor Naveed Sattar, professor of cardiometabolic medicine at the University of Glasgow, said some of the suggested benefits identified in the study had been confirmed in randomised controlled trials such as reduced risk of heart attack and stroke

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Importantly, however, particle design governs risk: surface-displayed antigens or certain chemistries can raise immunogenicity and, in rare cases, provoke severe hypersensitivity (including anaphylaxis), whereas encapsulation strategies tend to blunt immediate antigen recognition and are therefore often safer in vivo (206, 208)