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High doses (1,0002,000 mcg/day) may be recommended for those with impaired absorption

Oral dosing (500 mcg to 1 mg in capsules) targets gut-related conditions: IBS, leaky gut, NSAID-induced gastric damage

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This condition, known as leaky gut, allows yeast, toxins, and undigested particles to escape into the bloodstream, triggering immune reactions and systemic inflammation

In cellular models, 2012 was able to potently and effectively reduce the number of FAK-containing focal adhesions with a sub-micromolar IC 50 value of 0.80 M, which was on par with the K D of 0.8 M at the helix 23 FAT domain site