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After 5 months, she had lost nearly 50 lb, and her PHQ-9 score was 1 (with no change in antidepressant treatment)

However, if steroid injections only help temporarily, it is not advisable to repeat them regularly as they can have many potential side effects

The findings of the study showed that while blood levels of P-Cresol sulfate (PCS) considerably decreased along with a shift in the microbiota of the stool toward a healthier one, levels of indoxyl sulfate (IS) did not change as a result of the intervention (126)

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Second, visceral fat produces inflammatory chemicals that can weaken the lower oesophageal sphincter

Because DSIP may interact with neurotransmitter systems such as GABA and NMDA pathways, combining it with sedatives, alcohol, or other neuroactive substances could amplify drowsiness or increase the risk of neurological side effects