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The frequency varies by product and dosefor example, nausea affects approximately 20% of patients taking Ozempic but up to 44% of those on higher-dose Wegovy

O'Hara, A

Costa J, Wesley RA, Glatstein E, Rosenberg SA

Pros of GLP-1s: Non-surgical option Can lead to 1520% body weight loss in clinical trials May improve blood sugar, cholesterol, and inflammation Weekly injections, often self-administered Cons of GLP-1s: Real-world weight loss may be lower than clinical trials (510%) Side effects include nausea, vomiting, fatigue, and gastroparesis High cost and limited insurance coverage Weight may return if medication is stopped What is weight loss surgery

Study involved 204 patients in a year-long trial, showing significant brain volume preservation

Known Cardiovascular Effects of Retatrutide Retatrutide is associated with dose-dependent increases in resting heart rate and favourable surrogate markers such as reduced blood pressure and triglycerides, but no cardiovascular outcomes trial has been completed