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Ethics declarations Competing interests SJW is the founder of Ridgeline Therapeutics, HN is a paid employee of Ridgeline Therapeutics and, since manuscript submission, ADW has also become a paid employee of Ridgeline Therapeutics
Current therapeutic uses for MOTS-c With its combined effects on cellular metabolism, stress response, and longevity, MOTS-c has many of the same therapeutic uses as growth hormone secretagogues (substances that stimulate growth hormone secretion) such as CJC-1295, ipamorelin, and tesamorelin
Higher doses, such as 50,000 IU (1,250 mcg), may be recommended in cases of vitamin D deficiency under a doctors guidance
sterile water vs
adults with at least some familiarity with peptides as a health and wellness tool, fielded May 811, 2026