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Recommended Protocol for Post-Weight-Loss Skin Tightening Dosage: 2 mg daily subcutaneous injection Cycle length: 10 to 12 weeks Rest period: 4 to 6 weeks between cycles Injection sites: Rotate between abdomen, upper arms, and thighs Optional addition: Topical GHK-Cu serum (0.5 to 1%) applied to problem areas Cycles per year: 2 to 3 Subcutaneous injection is the preferred route for skin applications because it provides near 100% bioavailability and allows for easy self-administration using 29 to 31 gauge insulin syringes at a 45 to 90 degree angle

Oxidative stress is a major factor in signs of premature aging in skin

Le glutathion amplifie un terrain sain, il ne le cre pas

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Mitochondria are particularly vulnerable to oxidative and toxic stress, and in these cases, some clinicians are incorporating redox-modulating compounds such as methylene blue into personalized protocols, based on clinical judgment

Acta Med Scand 1982;212(3):115-120