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29 In terms of the nervous system, GLP-1 receptor (GLP-1R) expression is enriched in central nervous system (CNS) regions, including the hypothalamus, which regulates appetite, and the brainstem, which primarily secretes brain-derived GLP-1, as well as in the peripheral vagus nerve

Health Canada approves Victoza as the first and only GLP-1 receptor agonist to reduce the risk of cardiovascular death in patients with type 2 diabetes and established cardiovascular disease

One natural concern: glucagon normally raises blood sugar

Liraglutide Attenuates Cardiac Remodeling and Improves Heart Function After Abdominal Aortic Constriction Through Blocking Angiotensin II Type 1 Receptor in Rats

Researchers study retatrutide for obesity, type 2 diabetes, and related metabolic disorders such as NAFLD and MASH