Dietetic input is particularly valuable in older patients to ensure nutritional needs are met while achieving a calorie deficit
In clinical practice, drug selection should therefore prioritize factors such as tolerability, safety profile, adherence, cost, and patient preference rather than expecting major differences in cardiovascular efficacy
But the price point raises its own questions, particularly around who this serves and who it doesn't as coverage remains fragmented across the Canadian benefits landscape
Tesamorelin is the sledgehammer for fat reduction and Sermorelin offers a more foundational, broader approach
Moreover, the tryptophan derivative indole has been shown to promote enteroendocrine cells to secrete GLP-1 66,67
Texas, California, New York, Pennsylvania, and Illinois generally permit it if federal rules and standard of care are met