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Similarly, those with pancreatitis or significant GI diseases should consult for alternative methods

A P value less than 0.05 was considered statistically significant

PlexusDx eliminates this barrier with flat, transparent pricing: compounded semaglutide injection is $189/mo month-to-month (or $149/mo on the 6-month plan) regardless of whether you're on your starting dose or your maintenance dose

NovoCare (Novo Nordisks direct-to-patient program) advertises Wegovy pen self-pay at $199/month for the first two fills for new patients within a limited window, then $349/month thereafter, and Wegovy pill self-pay at $149/month for the 1.5 mg and 4 mg doses (with a documented offer change after April 15, 2026) and $299/month for the 9 mg and 25 mg doses

But their effectiveness varies widely

For qualifying patients, semaglutide may be incorporated into a personalized weight loss program alongside nutrition, physical activity and regular monitoring