Couples often spend an average of $61,377 out-of-pocket across 2.7 cycles to achieve a live birth, placing substantial financial and emotional strain on individuals and families ( Although pharmacological therapies retain their efficacy, dietary supplements, including coenzyme Q10 (CoQ10), myo-inositol, melatonin, and vitamins, have emerged as a promising adjunct in infertility management due to their potential to mitigate oxidative stress, improve hormonal balance, and enhance reproductive capacity ( Furthermore, while serum mineral supplementation has been associated with improved oocyte quality, supports embryo development, mitigates oxidative stress, regulates hormonal balance, and optimizes IVF outcomes, while concurrently reducing miscarriage rates ( Despite accumulating evidence, inconsistencies in findings related to macromolecule and nutrient intake highlight the need for clearer mechanistic insights

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A new mtDNA mutation in the tRNA(Lys) gene associated with myoclonic epilepsy and ragged-red fibers (MERRF) Am
M.WoesteS.HacheneyI.et al (2022)
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