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Cell 156 , 4568 (2014)

Various inherited and lifestyle factors contribute to vitamin B12 deficiencies that impair such fundamental life processes as recycling of homocysteine, a potentially toxic metabolite, nerve cell signaling, mood and memory management, and healthy gene regulation (epigenetics), from pregnancy through old age

11.1 +/- 1.1% with pramlintide + sibutramine, 11.3 +/- 0.9% with pramlintide + phentermine, -3.7 +/- 0.7% with pramlintide

Various physiological & pathological states, such as wound healing or regeneration after damage can be connected with these processes

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