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Moreover, all the animals habituated to the open-field boxes on three consecutive days prior to the testing, therefore minimizing the effects of novelty as a potential confounding factor

2.3 Acute oral toxicity study Acute oral toxicity study was designed based on the guidelines provided by the Organisation for Economic Co-operation and Development No.423 (OECD 423), Acute Oral Toxicity - Acute Toxic Class Method (OECD, 2002b)

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Then, patients move to monthly maintenance doses to keep B12 levels steady over time

Understanding Vitamin B12 What is Vitamin B12

Vitamin B6 has the ability to improve metabolism and the breakdown of protein