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Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: a phase 1b, multicentre, blinded, placebo-controlled, randomized, multiple-ascending-dose study in people with type 2 diabetes
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Clearly, mAb1-bound GCGR is unable to assume the closed conformation observed in the Fab7F38GLP-1R structure
Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists
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