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Furthermore, there is a relatively increased excretion of 11-oxycorticoid metabolites (421), which are biologically inactive compounds

All embryos were cultured using sequential culture medium (Vitrolife, Gothenburg, Sweden) in incubators at 37C under 5% O 2 , 6% CO 2 , and 89% N 2 conditions with high moisture until day 6

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Adding more compounds increases complexity and makes it harder to attribute effects or side effects to specific agents