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Importantly, any patch claiming to contain actual semaglutide, liraglutide, or other GLP-1 receptor agonists would be an unapproved, potentially illegal drug product in the US

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TABLE 1 Representative categories of underexplored peptidereceptor systems and primary barriers to therapeutic development

Owing to the short plasma half-life of native GLP1, several GLP1 receptor agonists (GLP1RAs) with longer half-lives have been developed for the treatment of T2DM

Over multiple draws from a single vial, dead volume losses accumulate