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The m -Dys-induced exercise intolerance with elevated arterial blood lactate levels and reduced fatty acid -oxidation rates is a major health issue in PASC 173

It utilizes homocysteine and serine to generate cystathionine ( -elimination reaction occurs, releasing a water (H 2 O) molecule and yielding an aminoacrylate intermediate

Short NJ, Montalban-Bravo G, Alvarado Y, Konopleva M, Jabbour EJ, Garcia-Manero G, Yilmaz M, Jain N, Borthakur G, DiNardo CD, Daver N, Issa GC, Ohanian M, Pemmaraju N, Sasaki K, Maiti A, Chien KS, Ravandi F, Kadia TM, Andreeff M , Muftuoglu M, Delumpa R, Bose P, Pierce SA, Waller L, Banks G, Kantarjian H, and Cortes JE

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