From a patient safety perspective, individuals should seek prompt medical advice if they experience: Severe or persistent abdominal pain (which may indicate pancreatitis) Right-upper-quadrant pain, fever, or jaundice (which may indicate a gallbladder problem) Rapid or irregular heartbeat Symptoms of hypoglycaemia, such as shakiness, sweating, or confusion Signs of an allergic reaction, such as rash, swelling, or difficulty breathing If you experience a suspected side effect from any medicine, you can report it to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk
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Rybelsus increases total thyroxine exposure by approximately 33%, necessitating thyroid function monitoring when starting or stopping treatment
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