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PMCID: PMC8504390

We also discuss challenges related to manufacturing scale-up, safety and toxicology, regulatory oversight, and consumer acceptance of nano-enabled nutraceuticals, and we present emerging trends such as co-encapsulation of synergistic ingredients and precision nutrition approaches

found that efficacy was consistent across mRNA, DNA, viral vectors, and inactive viruses and that differences in trial design, population characteristics and other factors were stronger contributors to heterogeneity than vaccine modality

For example, glutaminase inhibition using CB-839 was shown to increase the radiosensitivity of KEAP1/NRF2 mutant NSCLC in an in vitro model [25]