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Loss of muscle mass may occur on GLP-1s

Polymorphic variations in manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and catalase (CAT) contribute to elevated plasma triglyceride levels in Chinese patients with type 2 diabetes or diabetic cardiovascular disease

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Furthermore, with activation of normal PSCs, there is marked increase in the GLP-1R level

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