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Glycyrrhizin inhibits the metabolism of diosbulbin B (Yang et al., 2024), promotes bile acid efflux by increasing the expression of Nrf2/Farnesoid X Receptor- Bile Salt Export Pump (FXR-BSEP)/Multidrug Resistance-Associated Protein (MRP)2/P-glycoprotein/UDP-glucuronosyltransferase 1A1(UGT1A1), modulates gut microbiota, alleviates inflammation and oxidative stress, and improves diosbulbin B-induced liver injury (Wang et al., 2025)
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concluded that in the first year following a first cancer diagnosis, male cancer survivors have a 30% increased risk of developing prostate cancer as a SPC, partly due to increased diagnostic activity of the urological organs or incidental finding following health checkups 114
Fibrogenesis Tissue Repair 1 (1), 6
