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The most common side effects for retatrutide were gastrointestinal related, mostly mild to moderate in severity, and were partially mitigated with a lower starting dose

Taste disturbances (dysgeusia) are documented in the tirzepatide SmPC and can manifest as a metallic taste, altered flavour perception, or general taste changes that patients may associate with tongue discomfort

With consistent daily use, most customers notice the shift within two to four weeks

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HFD = high-fat diet