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Metabolomic profiling of CSF and blood serum elucidates general and sex-specific patterns for mild cognitive impairment and Alzheimer's disease patients

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In these reactions GSH is oxidized to GSSG and the ratio [GSH]/[GSSG], an indicator of the redox status of the cell, is known to regulate redox sensitive enzymes in the pathways for cell proliferation and cell apoptosis [5]

It all starts with Coenzyme A which is arguably the most important coenzyme in the body as it's involved in more than 100 different reactions (Source)