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Some Cough and Cold Medicines Some over-the-counter cough and cold medications contain ingredients that can interact with antidepressants, particularly MAOIs, says Kristi Mae Wragg, MD, an adult psychiatrist and director of outpatient services at HopeWay Psychiatry and Associates in Charlotte, North Carolina

Self-administering unregulated injectable substances carries serious risks, including infection, embolism, and systemic toxicity