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PS-MPs activate both protective (Nrf2-Keap1) and apoptotic (p53Bcl-2/Bax) pathways

Because danuglipron and orforglipron also did not alter anxiety-like behaviour in the open field test or elevated plus maze (Extended Data Fig

What matters is keeping it separated from a claim that the medication modifies the autoimmune disease itself

However, persistent or severe headaches warrant medical review to exclude other causes and ensure appropriate management

Decreased mortality, anti-inflammatory properties and neuroprotective effects can be beneficial in chronic substance use which is associated with neuroinflammation and oxidative stress

So, I think we would see a very disrupted labor market in the process