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This selectivity provides fat metabolism benefits with a more favorable side effect profile compared to systemic hormonal interventions
Yet, increased risk of diabetic ketoacidosis (DKA) in people with T1D limits the use of these therapies to improve blood sugar management or reduce the risk of complications
GLP-1 and insulin regulation of skeletal and cardiac muscle microvascular perfusion in type 2 diabetes
Those with a history of pancreatitis should be counseled that tirzepatide has not been studied in patients with a history of pancreatitis, and alternative therapies may be more appropriate
When discussing this medication with your GP, diabetes specialist, or pharmacist, you may hear it called semaglutide tablets or oral semaglutide to distinguish it from injectable formulations of the same active ingredient