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It refers to how many of the three incretin receptors (GLP-1R, GIPR, GCGR) the peptide activates

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Interestingly, with respect to selectivity and potential drug development, FhGST-S1 demonstrated a different inhibition profile to hGSTS11 (PGDS) when probed with a series of isoquinolyl inhibitors that were synthesised as previously described 24 (Supplementary Table 1)

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