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A controlled trial that included 90 subjects with NAFLD found those treated with 303 mg silibinin along with 10 mcg (400 IU) vitamin D and 15 mg vitamin E, twice daily for six months, were more likely to improve with regard to metabolic markers, oxidative stress, endothelial function, and NAFLD progression compared with those who were untreated

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Using gene expression data from the Broad Institute's measurement of 13,424 human genes, analysis revealed GHK increases gene expression in 59% of affected genes while suppressing expression in 41%

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