This dual action of stimulating insulin and inhibiting glucagon makes GLP-1 a powerful regulator of glucose metabolism
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Experimental procedure The rats were randomly allocated into five groups as follows: The control group underwent a sham operation and received subcutaneous (S.C.) injections of 44 mM sodium phosphate dibasic, 70 mM NaCl + 0.007% Tween 20 for 10 weeks once weekly