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These omissions may have led to incomplete retrieval of relevant primary studies and introduced selection bias

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Centella Asiatica 4X complex (Asiaticoside, Madecassic Acid, Asiatic Acid, Madecassoside) soothes sensitivity and strengthens the skin barrier , paired with 3-O-Ethyl Ascorbic Acid and Tocopherol that shield against oxidative stress

Myristoyl Pentapeptide-17 (keratin and skin renewal)

Data Gaps: Specific regulatory constraints for "metabolic" claims vary by region

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