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In a study published in the New England Journal of Medicine, participants who took semaglutide lost an average of 15% of their body weight, compared to a 2.4% weight loss in the placebo group

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Millions of patients have used tirzepatide since 2022, providing extensive real-world safety experience beyond controlled trials

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The hype is enormous -- which is exactly why I want to give you a clear-eyed, physician's take on what we actually know, what we don't, and what a responsible approach to this peptide looks like

Reasonable Consumer Standard: This article is written for a general adult consumer audience