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The content of C3G, the high predominant anthocyanin component in Chinese bayberry (Fang et al., 2006), was under detectable in leaves and YS, showed a low concentration in MS and flower, and increased during late fruit developmental stages reaching up to 110.85 mg/100 g FW (fresh weight) at S6, consistent with visual appearances (Figures 2A,B)
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S-adenosylmethionine (SAMe)
For example, a nanogel PMNG carrying the chemotherapy drug doxorubicin was prepared by crosslinking carboxymethyl chitosan (CMCS)-derived multiple metformin (PolyMetCMCS) with cystamine, and then coated with hyaluronic acid on its surface to form the nanogel D@HPMNG, which can effectively remodel the TME by reprogramming the phenotype of TAMs and recruiting intratumoral CD8 + T cells thereby significantly inhibiting tumor growth (198)
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