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J PharmacogPhytochem

MTHFR is a central gene in the methylation cycle and is a limiting factor for producing methyl groups from folate (vitamin B9)

Some clinical trials have investigated glutathiones effects on skin pigmentation, and there is limited evidence that high-dose glutathione supplementation may reduce melanin production over time

Its effectiveness has even led to its adoption as a preventative measure against tendinopathiesconditions characterised by the breakdown of tendon collagen due to overuse or sudden stress, particularly prevalent among athletes

Studies confirm the link between low GSH and cognitive impairment: Closely tied to this is glutathiones role in mitochondrial survival