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Clinicians should counsel patients that GI side effects during dose escalation may transiently reduce sexual interest before the longer-term hormonal benefits of weight loss accumulate

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Metformin improves insulin sensitivity and modestly curbs appetite, while Contrave targets the brains reward and hunger pathways

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The AltaVISC (Figure 1) is a two-step, low-force activation autoinjector with an actuation mechanism that is configurable to allow buttons, levers, push-on-skin or squeeze triggers